Nanomedical engineering: shaping future nanomedicines.

The Nanomedicine Revolution, Part 2

Introduction Nanomedicine is a rapidly growing area of medical research that is focused on developing nanoparticles (NPs) for prophylactic, diagnostic, and therapeutic applications.1 The unique properties of nanomedicines offer potential solutions for many of the current challenges in treating cancer, cardiovascular, and neuodegenerative diseases, as well as other illnesses.1–7 Many nanomedicin...

Beyond human subjects: risk, ethics, and clinical development of nanomedicines.

Clinical testing of nanomedicines presents two challenges to prevailing, human subject-centered frameworks governing research ethics. First, some nanomedical applications may present risk to persons other than research subjects. Second, pressures encountered in testing nanomedicines may present threats to the kinds of collaborations and collective activities needed for supporting clinical trans...

Calling for Improved Translation in Nanomedical Research

The use of nanoparticles as novel diagnostic and therapeutic tools has gained immense attention in the field of cancer management. Nano-based therapies offer numerous possibilities such as enhanced drug solubility and stability, extended circulation times, tissue, cell, organelle-specific targeting, early detection and monitoring of diseases, stimuli-controlled drug release and co-delivery of m...

Carbon nanotubes and graphene as emerging candidates in neuroregeneration and neurodrug delivery

Neuroregeneration is the regrowth or repair of nervous tissues, cells, or cell products involved in neurodegeneration and inflammatory diseases of the nervous system like Alzheimer's disease and Parkinson's disease. Nowadays, application of nanotechnology is commonly used in developing nanomedicines to advance pharmacokinetics and drug delivery exclusively for central nervous system pathologies...

Advances in Nanosheet Technology Towards Nanomedical Engineering